Mebeverine (Colospa) an antimuscarinic, belongs to a group of compounds known as musculotropic antispasmodics, which aid in relaxing the smooth muscle in the gut by its direct action on it, preventing nerve signals going to the intestine muscles which causes the gut muscle to relax, preventing painful muscle spasm(s). Colospa (Mebeverine) provides relief from: diarrhoea/constipation, which are associated with irritable bowel syndrome. abdominal pain bloating, wind cramps