This medicine is used for the management of the cholesterol levels in the body. Ezetimibe is a lipid-lowering compound that inhibits absorption of cholesterol at the border of the small intestine, reducing hepatic cholesterol and clearing it. Simvastatin is a statin that blocks the HMG-CoA enzyme in the liver, preventing cholesterol synthesis from occurring. It also leads to an increased expulsion of low-density lipoprotein - LDL [ bad@ cholesterol], reduces triglycerides [a kind of fat in the blood/fat tissue], and raises the production of high-density lipoprotein - HDL [ good@ cholesterol]. Vytorin lessens the chances of heart attack, stroke and circulatory problems that are caused by imbalance of cholesterol.